Rajiv Jalan Selected Research

Acetaminophen (Paracetamol)

1/2020	Metabolism and Effects on Endogenous Metabolism of Paracetamol (Acetaminophen) in a Porcine Model of Liver Failure.
12/2018	Long-term outcome in patients with acute liver failure.
3/2017	Porcine model characterizing various parameters assessing the outcome after acetaminophen intoxication induced acute liver failure.
1/2017	Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.
1/2017	Development of an organ failure score in acute liver failure for transplant selection and identification of patients at high risk of futility.
9/2015	Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study.
1/2015	Circulating microRNAs Reveal Time Course of Organ Injury in a Porcine Model of Acetaminophen-Induced Acute Liver Failure.
7/2013	Role of toll-like receptor 4 in mediating multiorgan dysfunction in mice with acetaminophen induced acute liver failure.
4/2013	A reproducible, clinically relevant, intensively managed, pig model of acute liver failure for testing of therapies aimed to prolong survival.
1/2012	Correlation of the intracranial pressure to the central venous pressure in the late phase of acute liver failure in a porcine model.

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Rajiv Jalan Research Topics

Disease

86	Fibrosis (Cirrhosis) 04/2024 - 11/2002
45	Acute-On-Chronic Liver Failure 04/2024 - 10/2002
38	Acute Liver Failure (Fulminant Hepatic Failure) 01/2020 - 01/2002
37	Inflammation (Inflammations) 11/2023 - 02/2004
32	Hepatic Encephalopathy 08/2022 - 11/2002
29	Liver Failure 12/2022 - 01/2002
27	Liver Diseases (Liver Disease) 11/2023 - 06/2002
23	Hyperammonemia 12/2022 - 08/2002
14	End Stage Liver Disease 01/2023 - 08/2002
13	Intracranial Hypertension 06/2013 - 10/2002
10	Alcoholic Hepatitis 01/2021 - 04/2003
9	Infections 11/2023 - 02/2004
9	Portal Hypertension 01/2019 - 01/2007
8	Liver Cirrhosis (Hepatic Cirrhosis) 08/2023 - 01/2008
8	Necrosis 01/2022 - 02/2004
8	Alcoholic Liver Cirrhosis (Alcoholic Cirrhosis) 06/2020 - 05/2004
8	Brain Diseases (Brain Disorder) 03/2015 - 10/2002
7	Hepatorenal Syndrome 01/2023 - 12/2002
7	Hepatocellular Carcinoma (Hepatoma) 08/2022 - 02/2004
7	Ascites 01/2022 - 01/2008
7	Hemorrhage 07/2013 - 06/2002
6	Non-alcoholic Fatty Liver Disease 07/2023 - 10/2018
6	Alcoholic Fatty Liver 01/2023 - 04/2018
6	Endotoxemia 01/2023 - 11/2007
6	Hyperemia 06/2012 - 06/2003
5	Disease Progression 08/2022 - 04/2013
5	Peritonitis 01/2022 - 08/2009
5	Bacterial Infections (Bacterial Infection) 01/2021 - 06/2013
5	Brain Edema (Cerebral Edema) 01/2020 - 07/2005
5	Sepsis (Septicemia) 01/2017 - 12/2004
4	Neoplasms (Cancer) 10/2022 - 01/2018
4	Coma (Comas) 01/2020 - 06/2007
4	Renal Insufficiency (Renal Failure) 12/2019 - 05/2012
4	Hypothermia 06/2012 - 06/2003
3	COVID-19 11/2023 - 08/2022
3	Mitochondrial Diseases (Mitochondrial Disease) 08/2023 - 01/2020
3	Sarcopenia 07/2023 - 01/2022
3	Autoimmune Hepatitis 01/2023 - 12/2021
3	Acidosis 12/2022 - 04/2013
3	Critical Illness (Critically Ill) 12/2022 - 11/2011
3	Hepatitis 01/2022 - 08/2020
3	Insulin Resistance 01/2018 - 11/2007
3	Thrombocytopenia (Thrombopenia) 03/2017 - 07/2013
3	Acute Kidney Injury (Acute Renal Failure) 02/2015 - 02/2003
3	Hyperventilation 06/2012 - 08/2003

Drug/Important Bio-Agent (IBA)

57	AmmoniaIBA 12/2023 - 08/2002
34	AlbuminsIBA 11/2023 - 10/2002
18	CytokinesIBA 06/2020 - 10/2002
12	Biomarkers (Surrogate Marker)IBA 11/2023 - 01/2007
11	Acetaminophen (Paracetamol)FDA LinkGeneric 01/2020 - 10/2002
10	Anti-Bacterial Agents (Antibiotics)IBA 04/2024 - 09/2010
10	Amino Acids FDA Link 01/2021 - 11/2002
9	CreatinineIBA 10/2023 - 01/2003
9	EnzymesIBA 07/2023 - 04/2006
9	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2005
9	SodiumIBA 01/2023 - 08/2003
9	ornithine phenylacetateIBA 01/2020 - 07/2009
8	LipopolysaccharidesIBA 04/2024 - 06/2007
8	SolutionsIBA 01/2023 - 03/2003
7	Urea (Carbamide)FDA LinkGeneric 07/2023 - 08/2002
7	BilirubinIBA 01/2020 - 10/2002
7	salicylhydroxamic acid (SHAM)IBA 03/2017 - 06/2007
5	Interleukin-6 (Interleukin 6)IBA 11/2023 - 02/2004
5	Lactulose (Duphalac)FDA LinkGeneric 01/2022 - 07/2004
5	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 12/2007
5	EndotoxinsIBA 01/2020 - 08/2007
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 08/2012 - 01/2003
4	Toll-Like Receptor 4IBA 01/2023 - 05/2012
4	C-Reactive ProteinIBA 01/2022 - 02/2004
4	Vasoconstrictor AgentsIBA 11/2016 - 01/2003
4	Acetylcysteine (Siran)FDA LinkGeneric 06/2012 - 12/2002
3	Messenger RNA (mRNA)IBA 11/2023 - 06/2007
3	TerlipressinIBA 01/2023 - 12/2002
3	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2023 - 03/2007
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2023 - 01/2019
3	LipidsIBA 04/2022 - 12/2015
3	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2022 - 03/2015
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 09/2007
3	GalactosamineIBA 12/2021 - 07/2010
3	AntioxidantsIBA 01/2020 - 04/2015
3	Rifaximin (L 105)FDA Link 10/2017 - 09/2010
3	Propofol (Diprivan)FDA LinkGeneric 06/2012 - 08/2003
3	Thiopental (Pentothal)FDA Link 06/2012 - 08/2003
3	Infliximab (Remicade)FDA Link 03/2012 - 04/2003
3	Glutamine (L-Glutamine)FDA Link 03/2009 - 08/2002
3	Isoleucine (L-Isoleucine)FDA Link 11/2008 - 01/2007
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2007 - 04/2003
3	Hemoglobins (Hemoglobin)IBA 02/2004 - 03/2003
2	Carbon Tetrachloride (Tetrachloromethane)IBA 04/2024 - 12/2021
2	VaccinesIBA 11/2023 - 04/2023
2	Human Serum Albumin FDA LinkGeneric 08/2023 - 01/2016

Therapy/Procedure

47	Therapeutics 04/2024 - 01/2002
40	Liver Transplantation 11/2023 - 10/2002
12	Transplantation 01/2022 - 10/2002
11	Ligation 04/2024 - 09/2002
8	Transjugular Intrahepatic Portasystemic Shunt 07/2020 - 06/2002
7	Surgical Portasystemic Shunt (Portosystemic Shunt) 11/2018 - 01/2008
6	Critical Care (Surgical Intensive Care) 01/2023 - 02/2008
4	Artificial Liver (Bioartificial Liver) 01/2016 - 01/2002
3	Stents 11/2006 - 11/2002